Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976697 | 0.87 | MAPT (0.41) | TAS1R3TAS1R1BIRC2MAPTHSD17B10 | |
| SCHEMBL30174611 | 0.84 | BIRC2 (0.54) | TAS1R3TAS1R1BIRC2EPHX1ACHE | |
| SCHEMBL4632006 | 0.82 | CHRNB2 (0.44) | TAS1R3TAS1R1BIRC2MAPTHSD17B10 | |
| SCHEMBL20683487 | 0.82 | CA1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL1696818 | 0.82 | CA1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL5744322 | 0.81 | TAS1R3 (0.41) | TAS1R3TAS1R1BIRC2MAPTHSD17B10 | |
| SCHEMBL2344660 | 0.81 | EPHX1 (0.44) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL9006019 | 0.80 | EPHX1 (0.43) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL2345217 | 0.80 | EPHX1 (0.43) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10703068 | 0.80 | TAS1R3 (0.44) | TAS1R3TAS1R1BIRC2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282594-A1 | BRANCHED AMINO ACIDS | Medivir UK Ltd (GB) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087821-A1 | BRANCHED AMINO ACIDS | MEDIVIR UK LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |