Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 7/20 | 0.34 |
| ▸ | HTR2B | P41595 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15273122 | 0.74 | MAOA (0.41) | MAOBMAOAPTGS2CA1RECQL | |
| SCHEMBL9037008 | 0.70 | MAOA (0.44) | MAOBMAOAPTGS2RIPK1CA1 | |
| SCHEMBL3334799 | 0.66 | MEN1 (0.43) | MAOBMAOAPTGS2CA1KDM4E | |
| SCHEMBL6976621 | 0.65 | LMNA (0.39) | TAAR1MAOBMAOATSHRRIPK1 | |
| SCHEMBL6268223 | 0.65 | MAOA (0.57) | MAOBMAOAPTGS2CA1RECQL | |
| SCHEMBL3484183 | 0.61 | MAPT (0.59) | MAOBMAOAPTGS2HTR2BCA1 | |
| SCHEMBL9072251 | 0.61 | SMN1; SMN2 (0.46) | TSHRKDM4EGAAMAPTLMNA | |
| SCHEMBL323323 | 0.60 | TAAR1 (1.00) | TAAR1MAPTKMT2A | |
| SCHEMBL9135091 | 0.59 | MAOA (0.61) | MAOBMAOACA1KDM4EMEN1 | |
| SCHEMBL19319878 | 0.59 | CA1 (0.78) | MAOBMAOACA1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |