Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 8/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435378 | 0.97 | PLAU (0.55) | PLAUCASP3RECQLTSHRHCRTR1 | |
| SCHEMBL6434561 | 0.97 | PLAU (0.55) | PLAUCASP3RECQLTSHRHCRTR1 | |
| SCHEMBL6437192 | 0.89 | CASP3 (0.49) | PLAUCASP3RECQLTSHRHCRTR1 | |
| Hydrochloric Acid SCHEMBL6437190 | 0.88 | CASP3 (0.48) | PLAUCASP3RECQLTSHRHCRTR1 | |
| SCHEMBL7375712 | 0.87 | PLAU (0.71) | PLAURECQLTSHRLMNA | |
| SCHEMBL6434405 | 0.87 | PLAU (0.71) | PLAURECQLTSHRLMNA | |
| Hydrochloric Acid SCHEMBL6435890 | 0.86 | PLAU (0.70) | PLAURECQLTSHRLMNA | |
| SCHEMBL6437421 | 0.85 | PLAU (0.70) | PLAURECQLTSHRHCRTR1HCRTR2 | |
| SCHEMBL6434295 | 0.84 | PLAU (0.70) | PLAURECQLTSHRHCRTR1HCRTR2 | |
| SCHEMBL6438651 | 0.84 | CASP3 (0.51) | PLAUCASP3RECQLTSHRHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077945-B1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER (US) | 2003-01-08 | — | — | EP | claimed |
| US-20030199440-A1 | Composition for the treatment of damaged tissue | PFIZER INC. | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199440-A1 | Composition for the treatment of damaged tissue | MMP1, SERPINE1, COL14A1 | PLAU 119/4885CASP3 866/4885RECQL 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.