Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | RABGGTB | P53611 | 1/20 | 0.48 |
| ▸ | RABGGTA | Q92696 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977791 | 1.00 | LMNA (0.63) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL6977799 | 1.00 | LMNA (0.63) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL11973569 | 0.88 | MMP2 (0.59) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL6981947 | 0.88 | MMP2 (0.59) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL11993568 | 0.81 | LMNA (0.51) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL6981036 | 0.80 | MMP2 (0.54) | MAPTALDH1A1NPSR1MMP2SMN1; SMN2 | |
| SCHEMBL8471111 | 0.78 | MMP2 (0.55) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL2600493 | 0.78 | MMP2 (0.55) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL6081659 | 0.78 | MMP2 (0.55) | LMNAMAPTCA1ALDH1A1TSHR | |
| SCHEMBL8471118 | 0.78 | MMP2 (0.55) | LMNAMAPTCA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724569-B1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | AVECIA LTD (GB) | 2003-03-12 | — | — | EP | disclosed |
| US-5703246-A | REACTING AN ORGANOMETALLIC COMPOUND WITH ORGANOSULFUR COMPOUND | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |