Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325387 | 0.74 | TSHR (0.41) | HSD17B10LMNAMAPTHTTTSHR | |
| SCHEMBL29062918 | 0.68 | CCR2 (0.35) | GRM2GGT1BLMTSHR | |
| SCHEMBL17929167 | 0.66 | HSD17B10 (0.42) | HSD17B10LMNAMAPTHTTTSHR | |
| SCHEMBL25660659 | 0.65 | ARG1 (0.42) | GRM2HSD17B10GGT1BLMLMNA | |
| SCHEMBL10685383 | 0.64 | GGT1 (0.38) | GRM2HSD17B10GGT1BLMMAPT | |
| SCHEMBL24027544 | 0.64 | BLM (0.32) | GRM2GGT1BLM | |
| SCHEMBL24027545 | 0.64 | BLM (0.32) | GRM2GGT1BLM | |
| SCHEMBL17930204 | 0.63 | HSD17B10 (0.42) | HSD17B10LMNAMAPTHTTTSHR | |
| SCHEMBL145905 | 0.62 | TSHR (0.46) | HSD17B10LMNAMAPTHTTTSHR | |
| Acetic Acid SCHEMBL2763491 | 0.62 | HSD17B10 (0.41) | HSD17B10LMNAMAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199533-A1 | Novel amino carboxy alkyl derivatives of barbituric acid | CURRY KENNETH (CA) | 2003-10-23 | — | — | US | disclosed |
| EP-1276727-A1 | NOVEL AMINO CARBOXY ALKYL DERIVATIVES OF BARBITURIC ACID | Curry, Kenneth (CA) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001079185-A1 | NOVEL AMINO CARBOXY ALKYL DERIVATIVES OF BARBITURIC ACID | CURRY KENNETH (CA) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199533-A1 | Novel amino carboxy alkyl derivatives of barbituric acid | GRM1, GRM3, GRM2 | GRM2 3/4885HSD17B10 2346/4885GGT1 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.