Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.53 |
| ▸ | CNR1 | P21554 | 5/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978209 | 0.83 | CNR1 (0.49) | CNR2CNR1ACHEKDM4ELMNA | |
| SCHEMBL6968036 | 0.82 | CNR1 (0.49) | CNR2CNR1ACHEKDM4ELMNA | |
| SCHEMBL6974448 | 0.80 | CNR1 (0.48) | CNR2CNR1ACHEKDM4ELMNA | |
| SCHEMBL8809942 | 0.78 | KDM4E (0.58) | CNR2CNR1ACHEKDM4ELMNA | |
| SCHEMBL6975318 | 0.77 | CNR1 (0.48) | CNR2CNR1ACHEKDM4EHTR2A | |
| SCHEMBL6969861 | 0.77 | CNR2 (0.44) | CNR2CNR1ACHEKDM4ELMNA | |
| SCHEMBL6969602 | 0.77 | CNR2 (0.52) | CNR2CNR1ACHEKDM4EMAPT | |
| SCHEMBL6966885 | 0.76 | KDM4E (0.50) | CNR2CNR1KDM4ELMNACYP1A2 | |
| SCHEMBL8812598 | 0.72 | MEN1 (0.50) | CNR2CNR1KDM4ELMNACYP1A2 | |
| SCHEMBL6975356 | 0.71 | LMNA (0.45) | KDM4ELMNACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |