Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.39 |
| ▸ | MAT2A | P31153 | 4/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | AOC2 | O75106 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6973682 | 0.99 | MCL1 (0.39) | MCL1PLA2G7MAT2AGABRA5GABRA1 | |
| SCHEMBL6979995 | 0.95 | MCL1 (0.44) | MCL1PLA2G7MAT2ATBXAS1PTAFR | |
| SCHEMBL1961296 | 0.90 | GABRA1 (0.36) | PLA2G7GABRA5GABRA1TBXAS1PTAFR | |
| SCHEMBL6971083 | 0.90 | PTGDR2 (0.36) | PLA2G7TBXAS1GRM2 | |
| SCHEMBL6970863 | 0.89 | CYP1A2 (0.39) | PLA2G7GABRA5GABRA1 | |
| SCHEMBL6983342 | 0.89 | MAT2A (0.44) | MCL1PLA2G7MAT2AGABRA5GABRA1 | |
| Hydrochloric Acid SCHEMBL6977314 | 0.89 | GABRA1 (0.36) | PLA2G7GABRA5GABRA1TBXAS1PTAFR | |
| SCHEMBL6979997 | 0.88 | MCL1 (0.42) | MCL1PLA2G7MAT2AGABRA5GABRA1 | |
| SCHEMBL6973785 | 0.87 | CYP11B1 (0.35) | TBXAS1KMT2A | |
| Sulfuric Acid SCHEMBL6983443 | 0.87 | GABRA1 (0.35) | MCL1PLA2G7GABRA5GABRA1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-6018046-A | SELECTIVE ACTION IN INHIBITING CYCLIC GMP-PHOSPHODIESTERASE (CGMP-PDE); PHARMACEUTICALS FOR TREATING DISEASES AGAINST WHICH THE INHIBITORY ACTION IS EFFECTIVE, SUCH AS PULMONARY HYPERTENSION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |