Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985862 | 0.87 | ALDH1A1 (0.78) | ALDH1A1LMNASMN1; SMN2GLO1KDM4E | |
| SCHEMBL9800657 | 0.87 | FFAR4 (0.62) | ALDH1A1LMNASMN1; SMN2PIK3CAGLO1 | |
| SCHEMBL6978649 | 0.86 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL6982196 | 0.86 | ALDH1A1 (0.76) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL6981076 | 0.86 | ALDH1A1 (0.76) | ALDH1A1LMNASMN1; SMN2PIK3CAKDM4E | |
| SCHEMBL10654161 | 0.86 | GAA (0.60) | ALDH1A1LMNASMN1; SMN2PIK3CAGLO1 | |
| SCHEMBL6979083 | 0.85 | SMN1; SMN2 (0.74) | ALDH1A1LMNASMN1; SMN2GLO1KDM4E | |
| SCHEMBL1040688 | 0.83 | ALDH1A1 (0.75) | ALDH1A1LMNASMN1; SMN2GLO1KDM4E | |
| SCHEMBL6089373 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2ALPLKMT2A | |
| SCHEMBL10655458 | 0.81 | AR (0.55) | ALDH1A1LMNASMN1; SMN2PIK3CAGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |