Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALPL | P05186 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | CKS1B | P61024 | 1/20 | 0.56 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985862 | 0.87 | ALDH1A1 (0.78) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL6981076 | 0.86 | ALDH1A1 (0.76) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL6982196 | 0.86 | ALDH1A1 (0.76) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL6978003 | 0.86 | ALDH1A1 (0.76) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL1040688 | 0.86 | ALDH1A1 (0.75) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL6979083 | 0.85 | SMN1; SMN2 (0.74) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL1790284 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL5340962 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2KDM4EALPL | |
| SCHEMBL2055421 | 0.81 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2HTTPOLB | |
| SCHEMBL9237538 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNASMN1; SMN2KDM4EALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |