Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 16/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981550 | 0.90 | BRD4 (0.57) | BRD4CREBBPNR3C1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6977752 | 0.89 | F2 (0.49) | BRD4CREBBPNR3C1 | |
| SCHEMBL6982740 | 0.88 | NR3C1 (0.59) | NR3C1SMN1; SMN2TP53MAPT | |
| SCHEMBL6979627 | 0.88 | NR3C1 (0.46) | BRD4CREBBPNR3C1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6981078 | 0.88 | NR3C1 (0.58) | NR3C1SMN1; SMN2TP53MAPT | |
| SCHEMBL6982230 | 0.87 | NR3C1 (0.47) | BRD4CREBBPNR3C1SMN1; SMN2MAPT | |
| Iodide SCHEMBL7959251 | 0.87 | NR3C1 (0.48) | BRD4CREBBPNR3C1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL6982102 | 0.87 | NR3C1 (0.48) | BRD4CREBBPNR3C1SMN1; SMN2 | |
| SCHEMBL6977631 | 0.87 | BRD4 (0.56) | BRD4CREBBPNR3C1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6980868 | 0.86 | NR3C1 (0.56) | NR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | claimed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | claimed |
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |