Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982230 | 0.90 | NR3C1 (0.47) | NR3C1BRD4CREBBPSMN1; SMN2TRIM24 | |
| SCHEMBL6978010 | 0.88 | BRD4 (0.54) | NR3C1BRD4CREBBPSMN1; SMN2 | |
| SCHEMBL6982740 | 0.88 | NR3C1 (0.59) | NR3C1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6981078 | 0.87 | NR3C1 (0.58) | NR3C1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6977752 | 0.87 | F2 (0.49) | NR3C1BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL6980868 | 0.86 | NR3C1 (0.56) | NR3C1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6980925 | 0.83 | NR3C1 (0.55) | NR3C1BRD4CREBBPSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6985450 | 0.82 | ADRB2 (0.56) | NR3C1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6975570 | 0.82 | NR3C1 (0.49) | NR3C1BRD4CREBBPTRIM24 | |
| Hydrochloric Acid SCHEMBL6977280 | 0.82 | NR3C1 (0.61) | NR3C1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | claimed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | claimed |
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |