Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6985449 | 0.99 | NR3C1 (0.40) | NR3C1F10F2PARP1RAB9A | |
| SCHEMBL7956926 | 0.93 | F2 (0.43) | NR3C1F10F2PARP1 | |
| SCHEMBL6976671 | 0.90 | F2 (0.41) | NR3C1F10F2ALDH1A1TP53 | |
| SCHEMBL6982923 | 0.88 | ALDH1A1 (0.40) | NR3C1F10RAB9AALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL6982383 | 0.87 | ALDH1A1 (0.39) | NR3C1F10F2RAB9AALDH1A1 | |
| SCHEMBL6976365 | 0.86 | NR3C1 (0.45) | NR3C1F10RAB9AALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL6977752 | 0.86 | F2 (0.49) | NR3C1F10F2 | |
| SCHEMBL6985022 | 0.84 | NR3C1 (0.40) | NR3C1F10F2PARP1RAB9A | |
| SCHEMBL6981747 | 0.81 | NR3C1 (0.44) | NR3C1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL6982622 | 0.81 | NR3C1 (0.38) | NR3C1F10F2PARP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | claimed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | claimed |
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |