Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697936 | 0.87 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1FDPS | |
| SCHEMBL697274 | 0.83 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30301958 | 0.78 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1FDPS | |
| SCHEMBL24827313 | 0.78 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1FDPS | |
| SCHEMBL697005 | 0.78 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL27753895 | 0.77 | HSD17B10 (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1FDPS | |
| SCHEMBL699102 | 0.76 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL697921 | 0.75 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30301935 | 0.75 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1FDPS | |
| SCHEMBL24826220 | 0.75 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |