Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698833 | 0.88 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL697875 | 0.87 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL696960 | 0.83 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL27845582 | 0.81 | ALDH1A1 (0.38) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL705643 | 0.78 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL696521 | 0.77 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL27827035 | 0.76 | ALDH1A1 (0.38) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL27826896 | 0.76 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL699209 | 0.75 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2FDPSTDP1 | |
| SCHEMBL697826 | 0.75 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2FDPSTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |