Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697921 | 0.88 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2NOTUMALDH1A1 | |
| SCHEMBL696521 | 0.87 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2NOTUMALDH1A1 | |
| SCHEMBL697005 | 0.86 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2NOTUMALDH1A1 | |
| SCHEMBL30301958 | 0.81 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2NOTUMALDH1A1 | |
| SCHEMBL24827313 | 0.81 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2NOTUMALDH1A1 | |
| SCHEMBL697274 | 0.81 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2NOTUMALDH1A1 | |
| SCHEMBL696698 | 0.81 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2NOTUMALDH1A1 | |
| SCHEMBL697255 | 0.77 | MEN1 (0.46) | RAB9ANPC1SMN1; SMN2BRD4LMNA | |
| SCHEMBL5851274 | 0.76 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL697875 | 0.76 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |