Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588674 | 0.81 | TAAR1 (0.50) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL2099512 | 0.81 | CHRM2 (0.66) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL6978760 | 0.80 | CHRM2 (0.53) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL28750710 | 0.79 | AOC3 (0.47) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL27894442 | 0.77 | MAOB (0.63) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL6978761 | 0.76 | GPR55 (0.46) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL2092574 | 0.76 | LTA4H (0.67) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL31739258 | 0.76 | LTA4H (0.67) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL980218 | 0.75 | — | — | |
| SCHEMBL14191204 | 0.74 | LTA4H (0.70) | CHRM2CHRM1CHRM3TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1222511-C | I-aryl-or-I-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-b ligands | WYETH CO (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1484638-A | I-aryl-or-I-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-b ligands | — | 2004-03-24 | — | — | CN | disclosed |
| EP-1343756-A2 | 1-ARYL- OR 1-ALKYLSULFONYL-HETEROCYCLYLBENZAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002036562-A2 | 1-ARYL- OR 1-ALKYLSULFONYL-HETEROCYCLYLBENZAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2002-05-10 | — | — | WO | disclosed |