Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 7/20 | 0.41 |
| ▸ | ADH1C | P00326 | 4/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957146 | 0.80 | ADH1A (0.42) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL14397102 | 0.74 | ADH1A (0.48) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL105488 | 0.74 | ADH1A (0.48) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL13503180 | 0.74 | ADH1A (0.48) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL8299579 | 0.72 | ADH1C (0.40) | ADH1AADH1CADH1BALDH1A1KDM4E | |
| SCHEMBL7862759 | 0.72 | ADH1B (0.36) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL104779 | 0.71 | ADH1A (0.44) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL9949553 | 0.70 | ADH1C (0.40) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL22271013 | 0.70 | ADH1A (0.40) | ADH1AADH1CADH1BTSHRALDH1A1 | |
| SCHEMBL20615275 | 0.70 | ADH1A (0.40) | ADH1AADH1CADH1BTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |
| EP-0400065-A4 | LHRH ANALOGS | — | 1991-03-13 | — | — | EP | claimed |
| EP-0413209-A1 | LHRH analogs | TAP Pharmaceuticals Inc. (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0400065-A1 | LHRH ANALOGS. | ABBOTT LAB (US) | 1990-12-05 | — | — | EP | claimed |
| WO-1989007450-A1 | LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328090-A2 | LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |