Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MGLL | Q99685 | 4/20 | 0.62 |
| ▸ | FAAH | O00519 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LGMN | Q99538 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862607 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL8655426 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL4397261 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL4399380 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL1108678 | 0.77 | MGLL (0.82) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL8984231 | 0.77 | MGLL (0.66) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL12590360 | 0.75 | ALDH1A1 (0.72) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL19380615 | 0.75 | MGLL (1.00) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL4391501 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MGLLFAAHMAPTHPGD | |
| SCHEMBL4394405 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MGLLFAAHMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107756-A4 | NOVEL ISOXAZOLINONE ANTIBACTERIAL AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2003-02-26 | — | — | EP | disclosed |
| US-20020094984-A1 | Novel isoxazolinone antibacterial agents | SNYDER LAWRENCE B (US) | 2002-07-18 | — | — | US | disclosed |
| US-6420349-B1 | POTENT ANTIBIOTIC ACTIVE AGAINST GRAM-POSITIVE BACTERIA; ANIMAL FEED;FOOD PRESERVATIVES; WATERBASED PAINTS; WHITE WATER OF PAPER MILLS; DISINFECTANTS FOR MEDICAL AND DENTAL EQUIPMENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-07-16 | — | — | US | disclosed |
| EP-1107756-A1 | NOVEL ISOXAZOLINONE ANTIBACTERIAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000010566-A1 | NOVEL ISOXAZOLINONE ANTIBACTERIAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094984-A1 | Novel isoxazolinone antibacterial agents | RPS4X, RPS4Y1, CYP51A1 | ALDH1A1 261/4885MGLL 3572/4885FAAH 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.