Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575032 | 0.81 | CUL4A (0.35) | HSD17B10ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL14288616 | 0.76 | TUBB4A (0.33) | HSD17B10MAPT | |
| SCHEMBL9574960 | 0.73 | DAO (0.41) | HSD17B10ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5887893 | 0.72 | HPGD (0.53) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL8189892 | 0.72 | POLB (0.40) | HSD17B10ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL17630168 | 0.72 | KDM4E (0.37) | HSD17B10ALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL6995150 | 0.71 | ALOX5 (0.34) | ALDH1A1KMT2AMAPT | |
| SCHEMBL6653372 | 0.71 | POLB (0.44) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL7509630 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KMT2AKDM4EMAPTCDK2 | |
| SCHEMBL28477031 | 0.71 | POLB (0.38) | ALDH1A1KMT2AMEN1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214316-B1 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INT LTD (CH) | 2003-05-07 | — | — | EP | disclosed |