SCHEMBL697905

SCHEMBL697905

CC(=O)c1cc(C)ccc1C

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
CSNK2A1 P68400 1/20 0.48
TSHR P16473 1/20 0.47
CYP2A6 P11509 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636568 1.00 KMT2A (0.55) KMT2AMEN1CSNK2A1TSHRCYP2A6
SCHEMBL471440 0.84 CSNK2A1 (0.69) KMT2AMEN1CSNK2A1TSHRHSD17B10
SCHEMBL29495347 0.84 CSNK2A1 (0.69) KMT2AMEN1CSNK2A1TSHRHSD17B10
SCHEMBL12986352 0.83 CSNK2A1 (0.50) KMT2AMEN1CSNK2A1CYP2A6SMN1; SMN2
SCHEMBL9862051 0.83 MEN1 (0.57) KMT2AMEN1CSNK2A1TSHRSMN1; SMN2
SCHEMBL9420245 0.83 MEN1 (0.57) KMT2AMEN1CSNK2A1TSHRSMN1; SMN2
SCHEMBL9969949 0.82 MEN1 (0.52) KMT2AMEN1CSNK2A1TSHRSMN1; SMN2
SCHEMBL223101 0.81 CSNK2A1 (0.65) KMT2AMEN1CSNK2A1TSHRSMN1; SMN2
SCHEMBL96218 0.81 KMT2A (0.51) KMT2AMEN1CSNK2A1CYP2A6SMN1; SMN2
SCHEMBL29381894 0.81 KMT2A (0.51) KMT2AMEN1CSNK2A1CYP2A6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325204-A Low-temperature-rise rubber and carbon black composition and preparation method thereof 华南理工大学 2024-07-12 CN claimed
US-9714560-B2 Protected scale inhibitors and methods relating thereto HALLIBURTON ENERGY SERVICES, INC. (US) 2017-07-25 US claimed
US-6444195-B1 MIXTURE OF DIBENZOYLMETHANE AND BENZOPHENONE COMPOUND JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2002-09-03 US claimed
WO-2002017873-A1 SUNSCREEN COMPOSITIONS CONTAINING A DIBENZOYLMETHANE DERIVATIVE AND A TRIAZINE DERIVATIVE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-07 WO claimed
WO-2002017872-A1 SUNSCREEN COMPOSITIONS CONTAINING TITANIUM DIOXIDE AND TRIAZINE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-07 WO claimed
CN-118325204-A Low-temperature-rise rubber and carbon black composition and preparation method thereof 华南理工大学 2024-07-12 CN disclosed
US-20240208912-A1 MTA-Cooperative PRMT5 Inhibitors MIRATI THERAPEUTICS INC (US) 2024-06-27 US disclosed
CN-117986153-A Ionizable cationic lipid compound, and preparation method and application thereof 晟迪生物医药(苏州)有限公司 2024-05-07 CN disclosed
CN-117568821-A Electrochemical synthesis method of quinoxaline derivative 齐齐哈尔医学院 2024-02-20 CN disclosed
WO-2023224998-A1 INHIBITORS OF PARG 858 THERAPEUTICS, INC. (US) 2023-11-23 WO disclosed
US-20230130025-A1 PHOTORESIST COMPOSITIONS AND METHODS FOR FABRICATING SEMICONDUCTOR DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2023-04-27 US disclosed
US-20230130025-A1 PHOTORESIST COMPOSITIONS AND METHODS FOR FABRICATING SEMICONDUCTOR DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2023-04-27 US disclosed
US-4665181-A Anti-inflammatory phthalazinones PENNWALT CORPORATION (US) 1987-05-12 US disclosed
US-4562067-A Preparation of novel dibenzoylmethane derivative sunscreen agents HAARMANN & REIMER GMBH (DE) 1985-12-31 US disclosed
EP-0164593-A1 Anti-inflammatory phthalazinones FISONS CORPORATION (US) 1985-12-18 EP disclosed
EP-0114607-B1 DIBENZOYL METHANE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE HAARMANN & REIMER GMBH (DE) 1985-09-04 EP disclosed
US-4489057-A DIBENZOYLMETHANE COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1984-12-18 US disclosed
EP-0114607-A1 Dibenzoyl methane derivatives, process for their production and their use HAARMANN & REIMER GMBH (DE) 1984-08-01 EP disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed
US-3931152-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208912-A1 MTA-Cooperative PRMT5 Inhibitors PRMT1, PRMT5, PRMT6 KMT2A 165/4885MEN1 677/4885CSNK2A1 388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.