SCHEMBL96218

SCHEMBL96218

CC(=O)c1ccc(C)cc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
CYP2A6 P11509 1/20 0.50
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
NFE2L2 Q16236 1/20 0.49
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HSD11B1 P28845 1/20 0.46
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
GLA P06280 1/20 0.45
MCL1 Q07820 1/20 0.45
HSD17B10 Q99714 1/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
MEN1 O00255 1/20 0.44
FLT1 P17948 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381894 1.00 KMT2A (0.51) KMT2ACYP2A6RAB9ANPC1NFE2L2
SCHEMBL31369141 0.83 LMNA (0.50) KMT2ARAB9ANPC1NFE2L2HTT
SCHEMBL9420260 0.83 NFE2L2 (0.55) KMT2ARAB9ANPC1NFE2L2HTT
SCHEMBL286054 0.83 LMNA (0.50) KMT2ARAB9ANPC1NFE2L2HTT
SCHEMBL12986352 0.83 CSNK2A1 (0.50) KMT2ACYP2A6RAB9ANPC1NFE2L2
SCHEMBL22078944 0.82 KMT2A (0.50) KMT2ARAB9ANPC1NFE2L2SMN1; SMN2
SCHEMBL29636568 0.81 KMT2A (0.55) KMT2ACYP2A6NPC1SMN1; SMN2KDM4E
SCHEMBL30679777 0.81 CSNK2A1 (0.59) KMT2ANFE2L2HTTSMN1; SMN2TP53
SCHEMBL697905 0.81 KMT2A (0.55) KMT2ACYP2A6NPC1SMN1; SMN2KDM4E
SCHEMBL107259 0.81 CSNK2A1 (0.59) KMT2ANFE2L2HTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 730 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325204-A Low-temperature-rise rubber and carbon black composition and preparation method thereof 华南理工大学 2024-07-12 CN claimed
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 EP claimed
CN-115925527-B Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2024-02-09 CN claimed
EP-2763541-B1 PEST CONTROL FORMULATIONS AND METHODS OF MAKING AND USING SAME 0903608 B C LTD (CA) 2023-06-07 EP claimed
CN-115925527-A Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2023-04-07 CN claimed
CN-108929400-B Nickel catalyst system, high-performance polybutadiene and preparation method thereof 北京化工大学 2023-03-14 CN claimed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-113912795-B Polyisomonoolefin copolymer, preparation method thereof, initiator and application 北京石油化工学院 2022-11-22 CN claimed
CN-114395064-A Preparation method for improving polymerization temperature of polyisomonoolefin-based elastomer or molecular weight of elastomer 北京石油化工学院 2022-04-26 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
US-6492563-B2 PROVIDES NON-VOLATILE PRECURSORS FOR VOLATILE FRAGRANT ESTERS FOR USE IN DETERGENT, A FABRIC SOFTENER, A WINDOW CLEANER, A HARD SURFACE CLEANER, AN ALL PURPOSE CLEANER, A FURNITURE POLISH, A SHAMPOO, A CONDITIONER, AN HAIRSPRAY, A COSMETIC GIVAUDAN SA (CH) 2002-12-10 US claimed
US-6444195-B1 MIXTURE OF DIBENZOYLMETHANE AND BENZOPHENONE COMPOUND JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2002-09-03 US claimed
US-20020077508-A1 Fragrance precursors GIVAUDAN SA (CH) 2002-06-20 US claimed
US-20020035055-A1 Fragrance precursors GIVAUDAN SA (CH) 2002-03-21 US claimed
EP-1167362-A1 Fragance precursors Givaudan SA (CH) 2002-01-02 EP claimed
EP-1146033-A2 Fragrance precursors Givaudan SA (CH) 2001-10-17 EP claimed
WO-1999002046-A1 FLAVOR ENHANCEMENT PROCESS SCHUR HENRY B (US) 1999-01-21 WO claimed
EP-0164593-B1 ANTI-INFLAMMATORY PHTHALAZINONES FISONS CORPORATION (US) 1989-11-15 EP claimed
EP-0164593-A1 Anti-inflammatory phthalazinones FISONS CORPORATION (US) 1985-12-18 EP claimed
EP-0161073-A2 Dyeing composition and its use in dyeing hair REPLIGEN CORPORATION (US) 1985-11-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077508-A1 Fragrance precursors ADH5, FAAH, CBR3 KMT2A 1139/4885CYP2A6 194/4885RAB9A 3089/4885
US-20020035055-A1 Fragrance precursors FAAH2, FDPS, CYP51A1 KMT2A 1306/4885CYP2A6 222/4885RAB9A 4566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.