Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 19/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979056 | 1.00 | OPRK1 (0.78) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL9510585 | 0.88 | OPRK1 (1.00) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL5629426 | 0.88 | OPRK1 (1.00) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL6977531 | 0.86 | OPRK1 (0.63) | OPRK1CYP2D6 | |
| SCHEMBL6977525 | 0.86 | OPRK1 (0.63) | OPRK1CYP2D6 | |
| SCHEMBL6975629 | 0.85 | OPRK1 (0.63) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL6975624 | 0.85 | OPRK1 (0.63) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL6974576 | 0.80 | OPRD1 (0.78) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL6974570 | 0.80 | OPRD1 (0.78) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 | |
| SCHEMBL8073905 | 0.79 | OPRD1 (0.77) | OPRK1CYP2D6CYP3A4TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | claimed |
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| WO-1996030339-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1996-10-03 | — | — | WO | disclosed |