Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 3/20 | 0.49 |
| ▸ | KIT | P10721 | 12/20 | 0.47 |
| ▸ | CSF1R | P07333 | 11/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966564 | 0.88 | HPGDS (0.65) | HPGDSBRAFKITCSF1RALDH1A1 | |
| SCHEMBL6972177 | 0.87 | HPGDS (0.60) | HPGDSBRAFKITCSF1RDDR1 | |
| SCHEMBL6782706 | 0.83 | HPGDS (0.75) | HPGDSBRAFKITCSF1REGFR | |
| SCHEMBL31721214 | 0.83 | HPGDS (0.65) | HPGDSBRAFKITCSF1RDDR1 | |
| SCHEMBL6780729 | 0.81 | HPGDS (0.67) | HPGDSBRAFKITCSF1REGFR | |
| SCHEMBL6972777 | 0.80 | HPGDS (0.55) | HPGDSBRAFKITCSF1RDDR1 | |
| SCHEMBL6976236 | 0.80 | HPGDS (0.55) | HPGDSBRAFKITCSF1RDDR1 | |
| SCHEMBL6973506 | 0.80 | HPGDS (0.64) | HPGDSBRAFKITCSF1RDDR1 | |
| SCHEMBL31721202 | 0.80 | HPGDS (0.69) | HPGDSBRAFKITCSF1RDDR1 | |
| SCHEMBL6968978 | 0.80 | MAPK14 (0.54) | HPGDSBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115707-B1 | BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2003-11-12 | — | — | EP | claimed |