Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983805 | 0.78 | CHRM1 (0.61) | SLC6A2SLC6A4SLC6A3CHRM1 | |
| SCHEMBL6030479 | 0.78 | SOS1 (0.56) | MAOAKDM1AMAOBSIGMAR1MEN1 | |
| Bromide SCHEMBL7978277 | 0.76 | SOS1 (0.54) | MAOAKDM1AMAOBSIGMAR1MEN1 | |
| Bromide SCHEMBL7978275 | 0.76 | SOS1 (0.54) | MAOAKDM1AMAOBSIGMAR1MEN1 | |
| Hydrochloric Acid SCHEMBL6984774 | 0.76 | SOS1 (0.54) | MAOAKDM1AMAOBSIGMAR1MEN1 | |
| SCHEMBL10460416 | 0.75 | TDP1 (0.50) | MAOAKDM1AMAOBTDP1HTR3E | |
| SCHEMBL4140224 | 0.75 | HTR6 (0.57) | MAOAKDM1AMAOBTDP1ALDH1A1 | |
| SCHEMBL22342849 | 0.73 | KDM1A (0.55) | KDM1AALDH1A1SLC6A4 | |
| SCHEMBL9533369 | 0.72 | TDP1 (0.47) | MAOAKDM1AMAOBTDP1ALDH1A1 | |
| SCHEMBL21788564 | 0.72 | TDP1 (0.47) | MAOAKDM1AMAOBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |