Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030479 | 0.81 | SOS1 (0.56) | CHRM1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6984774 | 0.80 | SOS1 (0.54) | CHRM1SLC6A2SLC6A4 | |
| Bromide SCHEMBL7978275 | 0.80 | SOS1 (0.54) | CHRM1SLC6A2SLC6A4 | |
| Bromide SCHEMBL7978277 | 0.80 | SOS1 (0.54) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL8400412 | 0.79 | HTR1D (0.43) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL6979082 | 0.78 | MAOA (0.51) | CHRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12715518 | 0.76 | CHRM1 (1.00) | CHRM1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Propane SCHEMBL27576811 | 0.75 | SOS1 (0.53) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL377433 | 0.72 | HTR6 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7319671 | 0.72 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |