Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046189 | 0.77 | CA2 (0.43) | PTPN1HPGDHSD17B10 | |
| SCHEMBL23888118 | 0.75 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL206233 | 0.74 | ALDH1A1 (0.46) | PTPN1HPGD | |
| SCHEMBL6716155 | 0.74 | KMT2A (0.42) | PTPN1 | |
| SCHEMBL30994107 | 0.73 | ALDH1A1 (0.33) | PTPN1 | |
| SCHEMBL20090022 | 0.71 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL15287525 | 0.71 | CA2 (0.33) | PTPN1HPGD | |
| SCHEMBL30573053 | 0.70 | ADRA2A (0.33) | PTPN1 | |
| SCHEMBL26601679 | 0.70 | ADRA2A (0.33) | PTPN1 | |
| SCHEMBL29493405 | 0.70 | PTPN1 (0.36) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |