Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 5/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | DPYD | Q12882 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585986 | 0.88 | LTA4H (0.59) | CYP4F2CYP4A11CYSLTR2CYSLTR1MGLL | |
| SCHEMBL6585897 | 0.86 | CYP4F2 (0.48) | CYP4F2CYP4A11CYSLTR2CYSLTR1MGLL | |
| SCHEMBL3165628 | 0.77 | CYP4F2 (0.81) | CYP4F2CYP4A11MGLLBCHELTA4H | |
| SCHEMBL3179250 | 0.77 | CYP4F2 (1.00) | CYP4F2CYP4A11MGLLBCHELTA4H | |
| SCHEMBL5760533 | 0.76 | CYP4F2 (0.79) | CYP4F2CYP4A11MGLLBCHELTA4H | |
| Hydrochloric Acid SCHEMBL11012160 | 0.76 | CYP4F2 (0.97) | CYP4F2CYP4A11MGLLBCHELTA4H | |
| SCHEMBL7615767 | 0.72 | CYP4F2 (0.88) | CYP4F2CYP4A11MGLLBCHELTA4H | |
| SCHEMBL5763262 | 0.71 | FFAR1 (0.70) | CYP4F2CYP4A11CYSLTR2CYSLTR1MGLL | |
| SCHEMBL7619322 | 0.71 | CYP4F2 (0.85) | CYP4F2CYP4A11MGLLBCHELTA4H | |
| SCHEMBL10554538 | 0.70 | PRMT5 (0.50) | CYP4F2CYP4A11LTA4HEPHX2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268473-A1 | OXAZOLE DERIVATIVES AND THEIR USES AS TYROSINE KINASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001077107-A1 | OXAZOLE DERIVATIVES AND THEIR USES AS TYROSINE KINASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-18 | — | — | WO | disclosed |