Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | DPYD | Q12882 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979240 | 0.86 | CYP4F2 (0.60) | CYP4F2CYP4A11CYSLTR2CYSLTR1MGLL | |
| SCHEMBL6976399 | 0.84 | CALM1 (0.37) | CYP4F2CYP4A11MGLL | |
| SCHEMBL6976396 | 0.76 | PPARA (0.40) | CYSLTR2CYSLTR1FFAR1MAOB | |
| SCHEMBL6585986 | 0.75 | LTA4H (0.59) | CYP4F2CYP4A11CYSLTR2CYSLTR1MGLL | |
| SCHEMBL6583968 | 0.71 | CYP4F2 (0.48) | CYP4F2CYP4A11MGLLBCHEFFAR1 | |
| SCHEMBL3165628 | 0.70 | CYP4F2 (0.81) | CYP4F2CYP4A11MGLLBCHEFFAR1 | |
| SCHEMBL5760533 | 0.69 | CYP4F2 (0.79) | CYP4F2CYP4A11MGLLBCHEFFAR1 | |
| SCHEMBL3179250 | 0.68 | CYP4F2 (1.00) | CYP4F2CYP4A11MGLLBCHEFFAR1 | |
| SCHEMBL5763262 | 0.67 | FFAR1 (0.70) | CYP4F2CYP4A11CYSLTR2CYSLTR1MGLL | |
| SCHEMBL7998538 | 0.67 | FFAR1 (0.69) | CYP4F2CYP4A11MGLLBCHEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116330-A1 | Diagnosing or specifying a growth factor receptor expressed in cancer cells, and selectively inhibiting all or a part of the growth factor receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-17 | — | — | US | disclosed |