Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 3/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966594 | 0.85 | TTK (0.46) | FADS1ALPLTTKALPILRRK2 | |
| SCHEMBL6974868 | 0.79 | TTK (0.50) | FADS1TTKGSK3BLRRK2AKR1B1 | |
| SCHEMBL7082179 | 0.77 | TTK (0.47) | FADS1TTKCNR2CNR1 | |
| SCHEMBL6975273 | 0.76 | MAPT (0.51) | TTKLRRK2CNR2GAA | |
| SCHEMBL6970859 | 0.75 | SMN1; SMN2 (0.49) | TTKLRRK2CNR2GAA | |
| SCHEMBL6978269 | 0.75 | MAPT (0.50) | TTK | |
| SCHEMBL6974524 | 0.74 | TTK (0.45) | FADS1TTKLRRK2CNR2GAA | |
| SCHEMBL6978830 | 0.73 | TTK (0.44) | FADS1TTKLRRK2CNR2CNR1 | |
| SCHEMBL6977777 | 0.73 | PRKAG1 (0.46) | TTKGSK3BCNR2GAA | |
| SCHEMBL17683325 | 0.71 | FADS1 (0.45) | FADS1LRRK2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-6166023-A | 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-26 | — | — | US | disclosed |