Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | FPR1 | P21462 | 2/20 | 0.52 |
| ▸ | FPR2 | P25090 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978707 | 0.98 | MAPT (0.58) | MAPTSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL6979722 | 0.85 | TP53 (0.48) | MAPTSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL6977395 | 0.85 | TP53 (0.46) | MAPTSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL4210381 | 0.84 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL6983746 | 0.83 | NR3C1 (0.47) | MAPK1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7407025 | 0.83 | NR3C1 (0.45) | MAPTSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL7959087 | 0.83 | TP53 (0.48) | MAPTSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL6976631 | 0.83 | HSD17B3 (0.46) | MAPTSMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL6986003 | 0.83 | RAB9A (0.48) | MAPTSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL6977738 | 0.83 | TP53 (0.51) | MAPTSMN1; SMN2MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |