Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981640 | 0.87 | NR3C1 (0.47) | NR3C1ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL6986976 | 0.87 | ADRB2 (0.58) | NR3C1ALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL6985290 | 0.86 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1CYP2C9MEN1 | |
| SCHEMBL6977969 | 0.85 | NR3C1 (0.56) | NR3C1ALDH1A1MEN1KMT2A | |
| SCHEMBL6985317 | 0.85 | NR3C1 (0.58) | NR3C1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6981743 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNAMAPK1NPSR1 | |
| SCHEMBL6977634 | 0.84 | NR3C1 (0.53) | NR3C1ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL6979462 | 0.83 | MAPT (0.58) | ALDH1A1TSHRMAPK1MEN1HPGD | |
| SCHEMBL6978707 | 0.83 | MAPT (0.58) | ALDH1A1TSHRMAPK1MEN1HPGD | |
| SCHEMBL6977395 | 0.82 | TP53 (0.46) | ALDH1A1TSHRLMNAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |