Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974395 | 0.75 | ALOX5 (0.36) | CTSDALOX5KCNA5 | |
| SCHEMBL8181137 | 0.75 | FFAR1 (0.34) | CTSDALOX5 | |
| SCHEMBL6980757 | 0.70 | MEN1 (0.39) | — | |
| SCHEMBL8175125 | 0.70 | KDM4E (0.33) | CTSDALOX5KCNA5 | |
| SCHEMBL4019894 | 0.67 | CRBN (0.36) | CTSDKCNA5 | |
| SCHEMBL6976465 | 0.66 | PTGS1 (0.41) | CTSD | |
| SCHEMBL23459341 | 0.65 | CTSD (0.58) | CTSD | |
| SCHEMBL6970123 | 0.65 | CTSD (0.58) | CTSD | |
| SCHEMBL6967526 | 0.65 | MPO (0.38) | CTSD | |
| SCHEMBL6967305 | 0.65 | OPRL1 (0.36) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | disclosed |
| US-6011028-A | Cyclic amidino agents useful as nitric oxide synthase inhibitors | G.D. SEARLE & CO. (US) | 2000-01-04 | — | — | US | disclosed |
| EP-0821674-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033175-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-10-24 | — | — | WO | disclosed |