Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983901 | 0.91 | ALDH1A1 (0.52) | RETCA1CA2MAPK14PLA2G2A | |
| SCHEMBL7685589 | 0.87 | MAPK14 (0.53) | RETCA1CA2MAPK14PLA2G2A | |
| SCHEMBL6978675 | 0.84 | MAPK14 (0.56) | RETCA1CA2MAPK14PLA2G2A | |
| SCHEMBL6978757 | 0.84 | PTGS2 (0.65) | MAPK14PLA2G2APLA2G4AALDH1A1RAB9A | |
| SCHEMBL6978284 | 0.83 | PTGS2 (0.63) | RETCA1CA2MAPK14PLA2G2A | |
| SCHEMBL6979358 | 0.81 | PTGS2 (0.67) | RETCA1CA2MAPK14PLA2G2A | |
| SCHEMBL7876427 | 0.79 | KDM4E (0.51) | CA1CA2MAPK14PLA2G2APLA2G4A | |
| SCHEMBL6977307 | 0.79 | KDM4E (0.55) | RETCA1CA2MAPK14PLA2G2A | |
| SCHEMBL6982123 | 0.79 | KDM4E (0.55) | RETCA1CA2MAPK14PLA2G2A | |
| SCHEMBL6974322 | 0.79 | PTGS2 (0.67) | RETCA1CA2MAPK14PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |