Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.31 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570147 | 0.86 | GAA (0.33) | GAAATMCOMTNPC1RAB9A | |
| SCHEMBL4678151 | 0.85 | COMT (0.40) | GAAATMCOMTNPC1RAB9A | |
| SCHEMBL4677779 | 0.83 | PPOX (0.43) | RAB9ANPBWR1MCHR1 | |
| SCHEMBL27413652 | 0.83 | DHODH (0.35) | GAAATMCOMTNPC1RAB9A | |
| SCHEMBL31448215 | 0.82 | NOTUM (0.37) | COMTCCR1 | |
| SCHEMBL4681846 | 0.82 | NOTUM (0.37) | COMTCCR1 | |
| SCHEMBL4679803 | 0.81 | PPOX (0.44) | GAANPBWR1MCHR1 | |
| SCHEMBL31442437 | 0.81 | PPOX (0.44) | GAANPBWR1MCHR1 | |
| SCHEMBL4678823 | 0.81 | PPOX (0.43) | GAANPBWR1MCHR1GRM2 | |
| SCHEMBL5843735 | 0.80 | HTT (0.45) | GAANPC1RAB9APAX8NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200428-B1 | SUBSTITUTED BENZOXAZOLES | BASF AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| EP-1200428-A1 | SUBSTITUTED BENZOXAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001012625-A2 | SUBSTITUTED BENZOXAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |