Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 3/20 | 0.45 |
| ▸ | XBP1 | P17861 | 3/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955767 | 0.82 | ALDH1A1 (0.45) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6979611 | 0.80 | GAA (0.33) | RAB9ANPC1PAX8GAANPBWR1 | |
| SCHEMBL6954881 | 0.79 | ALDH1A1 (0.50) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5843688 | 0.78 | SMN1; SMN2 (0.41) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5843154 | 0.78 | HTT (0.41) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5841555 | 0.78 | SMN1; SMN2 (0.50) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9665772 | 0.78 | RAB9A (0.50) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5841567 | 0.76 | RAB9A (0.42) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10413922 | 0.76 | P2RX7 (0.34) | MAPT | |
| SCHEMBL5842855 | 0.74 | RAB9A (0.40) | HTTRAB9AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012041-B2 | Phenylpyridazinones | BAYER AG (DE) | 2006-03-14 | — | — | US | disclosed |
| EP-0832072-B1 | PHENYLPYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2003-09-24 | — | — | EP | disclosed |
| US-20030119673-A1 | Phenylpyridazinones | LINKER KARL-HEINZ (DE) | 2003-06-26 | — | — | US | disclosed |
| US-6551963-B1 | For controlling unwanted vegetation | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| EP-0832072-A1 | PHENYLPYRIDAZINONES | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039392-A1 | PHENYLPYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119673-A1 | Phenylpyridazinones | CYP2D6, CYP1A1, CYP1B1 | HTT 2267/4885RAB9A 2247/4885ALDH1A1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.