Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 10/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679803 | 0.89 | PPOX (0.44) | PPOXNPBWR1MCHR1ALDH1A1MAPT | |
| SCHEMBL31442437 | 0.89 | PPOX (0.44) | PPOXNPBWR1MCHR1ALDH1A1MAPT | |
| SCHEMBL4678823 | 0.88 | PPOX (0.43) | PPOXNPBWR1MCHR1ALDH1A1 | |
| SCHEMBL27824325 | 0.87 | KDM4E (0.34) | PPOXNPBWR1MCHR1ALDH1A1RAB9A | |
| SCHEMBL8183347 | 0.85 | PPOX (0.32) | PPOXNPBWR1MCHR1LRRK2P2RX7 | |
| SCHEMBL27824328 | 0.85 | DHODH (0.32) | PPOXNPBWR1MCHR1ALDH1A1RAB9A | |
| SCHEMBL4248457 | 0.85 | PGK1 (0.35) | PPOXNPBWR1MCHR1LRRK2 | |
| SCHEMBL8183753 | 0.85 | PPOX (0.36) | PPOXNPBWR1MCHR1LRRK2P2RX7 | |
| SCHEMBL4681580 | 0.85 | LMNA (0.44) | PPOXALDH1A1MAPTPKMMAPK1 | |
| SCHEMBL8570147 | 0.84 | GAA (0.33) | NPBWR1MCHR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | claimed |
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-01-08 | — | — | US | claimed |
| US-6090753-A | 2-(SUBSTITUTED PHENYL), 5-HALOALKYL-PYRIDAZIN-3-ONE DERIVATIVES AS HERBICIDES; CONTROLLING WEEDS, METHOD OF MAKING BY REACTING A HYDRAZONE DERIVATIVE WITH A SPECIFIED PHOSPHORUS COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2000-07-18 | — | — | US | claimed |
| EP-0850227-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-01 | — | — | EP | claimed |
| WO-1997007104-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-27 | — | — | WO | claimed |
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-6869913-B1 | Pyridazin-3-one derivatives, their use and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-22 | — | — | US | disclosed |
| US-6703503-B2 | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-01-08 | — | — | US | disclosed |
| US-6482773-B1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-19 | — | — | US | disclosed |
| US-6348628-B1 | HYDRAZONE HERBICIDE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6090753-A | 2-(SUBSTITUTED PHENYL), 5-HALOALKYL-PYRIDAZIN-3-ONE DERIVATIVES AS HERBICIDES; CONTROLLING WEEDS, METHOD OF MAKING BY REACTING A HYDRAZONE DERIVATIVE WITH A SPECIFIED PHOSPHORUS COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0850227-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997007104-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | Q6ZSR9, HDHD5, CBR3 | PPOX 896/4885NPBWR1 2484/4885MCHR1 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.