Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.65 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659299 | 0.79 | PARP1 (1.00) | PARP1TNKSTNKS2KDM4ETYMS | |
| SCHEMBL29964360 | 0.79 | PARP1 (1.00) | PARP1TNKSTNKS2KDM4ETYMS | |
| SCHEMBL12309239 | 0.77 | KDM4E (0.45) | PARP1KDM4ELMNAHSD17B10 | |
| SCHEMBL30395697 | 0.76 | PARP1 (0.66) | PARP1TNKSTNKS2TYMSMMP13 | |
| SCHEMBL578200 | 0.76 | PARP1 (0.66) | PARP1TNKSTNKS2TYMSMMP13 | |
| SCHEMBL17298073 | 0.75 | PARP1 (0.65) | PARP1TNKSTNKS2KDM4ETYMS | |
| SCHEMBL2614349 | 0.73 | KDM4E (0.62) | PARP1TNKSTNKS2KDM4EMAPT | |
| SCHEMBL3126112 | 0.72 | PARP1 (0.60) | PARP1TNKSTNKS2KDM4ELMNA | |
| SCHEMBL13453668 | 0.72 | KDM4E (0.44) | PARP1KDM4ELMNAHSD17B10 | |
| SCHEMBL31523640 | 0.72 | PARP1 (0.60) | PARP1TNKSTNKS2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130602-A1 | INHIBITORS OF C. DIFFICILE SPORE GERMINATION | THE BOARDS OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2023-04-27 | — | — | US | disclosed |
| US-20230130602-A1 | INHIBITORS OF C. DIFFICILE SPORE GERMINATION | THE BOARDS OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2023-04-27 | — | — | US | disclosed |
| US-8183276-B2 | Therapeutic agents | MERCK SHARP & DOHME CORP. | 2012-05-22 | — | — | US | disclosed |
| US-20100324029-A1 | THERAPEUTIC AGENTS | MERCK SHARP & DOHME CORP. | 2010-12-23 | — | — | US | disclosed |
| US-20100324029-A1 | THERAPEUTIC AGENTS | MERCK SHARP & DOHME CORP. | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230130602-A1 | INHIBITORS OF C. DIFFICILE SPORE GERMINATION | CDC37, SI, DAD1 | PARP1 4316/4885TNKS 2943/4885TNKS2 3469/4885 |
| US-20100324029-A1 | THERAPEUTIC AGENTS | PSEN2, PSEN1, BACE2 | PARP1 1371/4885TNKS 2301/4885TNKS2 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.