Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 4/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979703 | 1.00 | FDPS (0.53) | FDPSTTRAKR1B10AKR1B1ALOX5 | |
| SCHEMBL6984691 | 0.85 | FDPS (0.57) | FDPSTTRRAB9ACYP3A4KDM4E | |
| SCHEMBL6984693 | 0.85 | FDPS (0.57) | FDPSTTRRAB9ACYP3A4KDM4E | |
| SCHEMBL6980403 | 0.83 | AKR1B10 (0.50) | FDPSTTRAKR1B10AKR1B1ALOX5 | |
| SCHEMBL6980407 | 0.83 | AKR1B10 (0.50) | FDPSTTRAKR1B10AKR1B1ALOX5 | |
| SCHEMBL16096495 | 0.81 | ALDH1A1 (0.48) | RAB9AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL6980418 | 0.81 | FDPS (0.64) | FDPSTTRMEN1ALDH1A1LMNA | |
| SCHEMBL6980423 | 0.81 | FDPS (0.64) | FDPSTTRMEN1ALDH1A1LMNA | |
| SCHEMBL6984784 | 0.79 | MAPT (0.60) | TTRRAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL6980310 | 0.78 | TTR (0.51) | FDPSTTRRAB9ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1292585-A1 | BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098282-A1 | BENZOXAZEPINONES AND THEIR USE AS SQUALENE SYNTHASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | SQLE, CYP17A1, ACOX1 | FDPS 296/4885TTR 4715/4885AKR1B10 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.