Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279724 | 0.87 | ESR1 (0.47) | NPC1MAPTRAB9ASMN1; SMN2ERN1 | |
| SCHEMBL6984271 | 0.84 | NPC1 (0.52) | NPC1MAPTRAB9AGFERHSD17B1 | |
| SCHEMBL4744425 | 0.81 | CA12 (0.47) | MAPTSMN1; SMN2WEE1ERN1ESR1 | |
| SCHEMBL5035375 | 0.81 | ESR1 (0.47) | NPC1RAB9ASMN1; SMN2ERN1HSD17B1 | |
| SCHEMBL5039825 | 0.81 | LSS (0.43) | GSK3BRPS6KA3MAPTSMN1; SMN2ERN1 | |
| SCHEMBL6279648 | 0.78 | NOD2 (0.50) | NPC1MAPTRAB9ASMN1; SMN2ESR1 | |
| SCHEMBL6984133 | 0.76 | MAPT (0.44) | PDGFRBPDGFRANPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6981985 | 0.74 | MAPT (0.43) | PDGFRBPDGFRANPC1MAPTRAB9A | |
| SCHEMBL6985680 | 0.74 | CYP19A1 (0.50) | NPC1MAPTRAB9AGFERPIK3CA | |
| SCHEMBL21295936 | 0.74 | CYP2A6 (0.47) | NPC1MAPTRAB9AGFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | QPCT 490/4885PDGFRB 1875/4885PDGFRA 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.