Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985095 | 0.92 | CYP11B1 (0.45) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| SCHEMBL6985848 | 0.91 | DYRK1A (0.50) | CYP19A1CYP11B1CYP11B2CYP3A4CYP17A1 | |
| SCHEMBL6981139 | 0.90 | CYP3A4 (0.54) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6985047 | 0.90 | CYP11B1 (0.44) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| SCHEMBL6984271 | 0.90 | NPC1 (0.52) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| SCHEMBL6989142 | 0.88 | CYP17A1 (0.50) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| SCHEMBL6985775 | 0.88 | MAPT (0.55) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6987641 | 0.86 | CYP17A1 (0.52) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| SCHEMBL6982148 | 0.84 | CYP11B2 (0.52) | CYP19A1CYP11B1CYP11B2MAPTNPC1 | |
| SCHEMBL6987081 | 0.84 | MAP3K7 (0.40) | CYP11B1CYP3A4CYP2D6CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | CYP19A1 17/4885CYP11B1 8/4885CYP11B2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.