Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979577 | 0.82 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL6977365 | 0.82 | P2RX7 (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA | |
| SCHEMBL2412938 | 0.82 | P2RX7 (0.49) | P2RX7PDE9A | |
| Sulfoxaflor SCHEMBL29688368 | 0.81 | LGMN (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA | |
| Sulfoxaflor SCHEMBL18103859 | 0.81 | LGMN (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA | |
| Sulfoxaflor SCHEMBL14148160 | 0.81 | LGMN (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA | |
| Sulfoxaflor SCHEMBL520711 | 0.81 | LGMN (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA | |
| Sulfoxaflor SCHEMBL18103858 | 0.81 | LGMN (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA | |
| Sulfoxaflor SCHEMBL686361 | 0.81 | LGMN (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA | |
| Sulfoxaflor SCHEMBL230364 | 0.81 | LGMN (0.37) | P2RX7LGMNKCNH2MAP4K4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8017788-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017788-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-08 | — | — | US | disclosed |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-08 | — | — | US | disclosed |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100168172-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-01 | — | — | US | disclosed |
| US-20100168172-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-01 | — | — | US | disclosed |
| US-7705156-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705156-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| WO-2008057131-A1 | HETEROARYL (SUBSTITUTED) ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | STS, DDT, TST | P2RX7 3063/4885LGMN 1377/4885KCNH2 3033/4885 |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | P2RX7 3063/4885LGMN 1377/4885KCNH2 3033/4885 |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | P2RX7 3063/4885LGMN 1377/4885KCNH2 3033/4885 |
| US-20100168172-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | P2RX7 3063/4885LGMN 1377/4885KCNH2 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.