Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757635 | 0.83 | MAPT (0.53) | MAPTLMNAL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL5806540 | 0.80 | MMP9 (0.54) | MAPTLMNAL3MBTL1MAPK1TP53 | |
| SCHEMBL5758844 | 0.72 | MAPT (0.56) | MAPTLMNATP53ALDH1A1THRB | |
| SCHEMBL5754134 | 0.72 | HTT (0.52) | MAPTTP53ALDH1A1THRBHTT | |
| SCHEMBL5756019 | 0.70 | MAPT (0.53) | MAPTLMNATP53ALDH1A1THRB | |
| SCHEMBL6966735 | 0.69 | MMP13 (0.55) | — | |
| SCHEMBL5756325 | 0.69 | HTT (0.55) | TP53ALDH1A1THRBHTT | |
| SCHEMBL9353698 | 0.67 | MAPT (0.67) | MAPTLMNAL3MBTL1MAPK1TP53 | |
| SCHEMBL5755465 | 0.66 | PPARG (0.45) | MAPTLMNAL3MBTL1TP53HTT | |
| SCHEMBL5756259 | 0.66 | ALOX15 (0.53) | TP53ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-A4 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1208092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001077092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-10-18 | — | — | WO | disclosed |