SCHEMBL6980491

SCHEMBL6980491

Cc1cc2ccc(N)cc2o1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.52
DYRK1A Q13627 1/20 0.46
ALDH1A1 P00352 9/20 0.43
KDM4E B2RXH2 9/20 0.43
HSD17B10 Q99714 7/20 0.43
HPGD P15428 5/20 0.43
CASP1 P29466 5/20 0.43
GAA P10253 4/20 0.43
CASP7 P55210 4/20 0.43
GLA P06280 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
PSMB8 P28062 1/20 0.41
LMNA P02545 3/20 0.39
POLB P06746 1/20 0.39
CASP6 P55212 1/20 0.39
MAPT P10636 7/20 0.39
SMN1; SMN2 Q16637 6/20 0.39
RAB9A P51151 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2790760 0.83 DYRK1A (0.59) CA2DYRK1AALDH1A1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL2482195 0.81 DYRK1A (0.58) CA2DYRK1AALDH1A1KDM4EHSD17B10
Dimethylamine SCHEMBL2103953 0.78 DYRK1A (0.54) CA2DYRK1AALDH1A1KDM4EHSD17B10
SCHEMBL806492 0.77 ALDH1A1 (0.50) DYRK1AALDH1A1KDM4EHSD17B10HPGD
SCHEMBL9018982 0.77 CA2 (0.55) CA2ALDH1A1KDM4EHSD17B10HPGD
SCHEMBL29384323 0.76 HSD17B3 (0.64) CA2ALDH1A1KDM4EHSD17B10HPGD
SCHEMBL534918 0.76 HSD17B3 (0.64) CA2ALDH1A1KDM4EHSD17B10HPGD
SCHEMBL8155015 0.74 CA12 (0.50) DYRK1AALDH1A1KDM4EHPGDCA12
SCHEMBL2269879 0.74 HSD17B3 (0.61) CA2ALDH1A1KDM4EHSD17B10HPGD
SCHEMBL8290256 0.74 APP (0.44) DYRK1AALDH1A1KDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266848-B1 ORGANIC LIGHT-EMITTING ELEMENT CAPABLE OF LOW-VOLTAGE DRIVE AND HAVING LONG LIFE SFC CO LTD (KR) 2019-07-31 EP disclosed
US-8026239-B2 Cell differentiation inducer BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-09-27 US disclosed
US-8026239-B2 Cell differentiation inducer BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-09-27 US disclosed
US-20100256201-A1 CELL DIFFERENTIATION INDUCER BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-10-07 US disclosed
US-20100256201-A1 CELL DIFFERENTIATION INDUCER BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-10-07 US disclosed
US-7687525-B2 Cell differentiation inducer BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-03-30 US disclosed
US-7687525-B2 Cell differentiation inducer BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-03-30 US disclosed
US-RE40703-E1 Cell differentiation inducer, benzamide compounds SCHERING AKTIENGESELLSCHAFT (DE) 2009-04-28 US disclosed
US-RE40703-E1 Cell differentiation inducer, benzamide compounds SCHERING AKTIENGESELLSCHAFT (DE) 2009-04-28 US disclosed
US-20080188489-A1 Cell differentiation inducer SCHERING AKTIENGESELLSCHAFT (DE) 2008-08-07 US disclosed
US-7317028-B2 Cell differentiation inducer SCHERING AKTIENGESELLSCHAFT (DE) 2008-01-08 US disclosed
US-7317028-B2 Cell differentiation inducer SCHERING AKTIENGESELLSCHAFT (DE) 2008-01-08 US disclosed
US-RE39754-E1 Benzamide derivatives and pharmaceutical compositions containing same SCHERING AG (DE) 2007-07-31 US disclosed
US-RE39754-E1 Benzamide derivatives and pharmaceutical compositions containing same SCHERING AG (DE) 2007-07-31 US disclosed
CN-1191063-C Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders GENENTECH INC (US) 2005-03-02 CN disclosed
US-6544981-B2 Anticoagulants, cardiovascular disorders BRISTOL-MYERS SQUIBB COMPANY 2003-04-08 US disclosed
EP-1294716-A1 LACTAM INHIBITORS OF FACTOR XA AND METHOD Bristol-Myers Squibb Company (US) 2003-03-26 EP disclosed
US-20020025957-A1 Lactam inhibitors of factor Xa and method BRISTOL-MYERS SQUIBB COMPANY 2002-02-28 US disclosed
WO-2001096331-A1 LACTAM INHIBITORS OF FACTOR XA AND METHOD BRISTOL-MYERS SQUIBB COMPANY (US) 2001-12-20 WO disclosed
CN-1295471-A Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders GENENTECH INC (US) 2001-05-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188489-A1 Cell differentiation inducer MCL1, MYADM, MYD88 CA2 1116/4885DYRK1A 3283/4885ALDH1A1 312/4885
US-20100256201-A1 CELL DIFFERENTIATION INDUCER MCL1, MYADM, MYD88 CA2 1185/4885DYRK1A 3315/4885ALDH1A1 296/4885
US-20020025957-A1 Lactam inhibitors of factor Xa and method F9, F7, F11 CA2 3830/4885DYRK1A 4096/4885ALDH1A1 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.