Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975226 | 0.82 | SLC18A3 (0.43) | POLB | |
| SCHEMBL8806149 | 0.81 | POLB (0.58) | POLB | |
| SCHEMBL6978104 | 0.81 | SLC18A3 (0.42) | POLB | |
| SCHEMBL6976167 | 0.79 | — | — | |
| SCHEMBL6981221 | 0.79 | POLB (0.45) | POLB | |
| SCHEMBL6971983 | 0.77 | CTSD (0.40) | HRH4HRH3 | |
| SCHEMBL6980494 | 0.77 | LTA4H (0.38) | TSHRHRH4HRH3POLB | |
| SCHEMBL6976719 | 0.77 | POLB (0.59) | POLB | |
| SCHEMBL4068078 | 0.75 | SIGMAR1 (0.53) | TSHRHRH3 | |
| SCHEMBL6609328 | 0.74 | POLB (0.59) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |