Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798960 | 0.82 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL6976741 | 0.75 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL8550044 | 0.75 | NOS3 (0.47) | NOS3NOS1NOS2 | |
| SCHEMBL7620769 | 0.74 | — | — | |
| SCHEMBL7618513 | 0.74 | NOS1 (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL8546560 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL7370736 | 0.72 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL6972927 | 0.72 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL7628313 | 0.71 | NOS1 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL6977209 | 0.71 | HRH3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | disclosed |
| EP-0821674-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033175-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-10-24 | — | — | WO | disclosed |