Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969989 | 0.80 | FFAR1 (0.32) | FFAR1PTGS1PTGS2PRKCZ | |
| SCHEMBL8181137 | 0.80 | FFAR1 (0.34) | FFAR1PTGS1PTGS2 | |
| SCHEMBL6976231 | 0.74 | KDM4E (0.34) | — | |
| SCHEMBL6975081 | 0.70 | FFAR1 (0.38) | FFAR1PTGS1PTGS2PRKCZ | |
| SCHEMBL6978959 | 0.67 | PTGS1 (0.42) | PTGS1PTGS2 | |
| SCHEMBL6980522 | 0.67 | MPO (0.39) | — | |
| SCHEMBL6977100 | 0.67 | KDM4E (0.31) | — | |
| SCHEMBL29051504 | 0.66 | PTGS1 (0.41) | FFAR1PTGS1PTGS2PRKCZ | |
| SCHEMBL6976719 | 0.63 | POLB (0.59) | — | |
| SCHEMBL6981221 | 0.62 | POLB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |