Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662145 | 0.89 | P2RX4 (0.43) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL6979690 | 0.82 | MEN1 (0.36) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL6974173 | 0.81 | MGLL (0.39) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL6976283 | 0.81 | CA1 (0.43) | KDM4EALDH1A1HPGDCYP19A1RORC | |
| SCHEMBL6975999 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL6979022 | 0.77 | PGR (0.39) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL13703591 | 0.77 | ALKBH5 (0.39) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL6976281 | 0.76 | NPC1 (0.41) | KDM4EALDH1A1MAPTMEN1HPGD | |
| SCHEMBL4512211 | 0.76 | ALKBH5 (0.41) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL31190839 | 0.76 | ALKBH5 (0.41) | KDM4EPOLBALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |