Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385056 | 0.88 | ITGB3 (0.45) | ALDH1A1ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL6985677 | 0.84 | ATM (0.50) | ALDH1A1ITGB1ITGA4CA1CA2 | |
| SCHEMBL6978962 | 0.77 | POLB (0.51) | ALDH1A1NPSR1POLBATM | |
| SCHEMBL8906494 | 0.75 | CA1 (0.46) | FOLH1CA1CA2POLBITGB3 | |
| SCHEMBL8906500 | 0.75 | CA1 (0.46) | FOLH1CA1CA2POLBITGB3 | |
| SCHEMBL6978278 | 0.75 | KMT2A (0.47) | NPSR1ITGB1FPR2ITGAVPOLB | |
| SCHEMBL7321784 | 0.74 | ITGB3 (0.48) | FOLH1FPR2CA1CA2ITGB3 | |
| SCHEMBL7862257 | 0.74 | KMT2A (0.41) | NPSR1FOLH1ITGB1ITGA5CA1 | |
| SCHEMBL8895885 | 0.73 | TSHR (0.46) | ALDH1A1POLB | |
| SCHEMBL7423126 | 0.72 | POLB (0.45) | NPSR1CA1CA2POLBITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | claimed |