Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.45 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.45 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379892 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BITGAVPOLBITGB5 | |
| SCHEMBL6352863 | 0.84 | ITGB3 (0.74) | ITGB3ITGA2BITGAVPOLBITGB5 | |
| SCHEMBL6980684 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7353558 | 0.82 | ITGB3 (0.65) | ITGB3ITGA2BPOLB | |
| SCHEMBL6985677 | 0.80 | ATM (0.50) | ITGB3ITGA2BATMPOLB | |
| SCHEMBL6985451 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BPOLB | |
| SCHEMBL8906500 | 0.77 | CA1 (0.46) | ITGB3ITGA2BPOLB | |
| SCHEMBL8906494 | 0.77 | CA1 (0.46) | ITGB3ITGA2BPOLB | |
| SCHEMBL7345488 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BATMPOLB | |
| SCHEMBL6983379 | 0.76 | ITGB3 (0.69) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | claimed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | claimed |
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |