Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.69 |
| ▸ | ITGAV | P06756 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390838 | 0.91 | ITGB3 (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL7391732 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL7353558 | 0.89 | ITGB3 (0.65) | ITGB3ITGA2BKMT2A | |
| SCHEMBL9389706 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL7384981 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL9394280 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BITGAV | |
| SCHEMBL6978255 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL8072019 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BITGAVKMT2ATDP1 | |
| SCHEMBL8075987 | 0.81 | KMT2A (0.58) | KMT2ATDP1 | |
| SCHEMBL7972470 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | claimed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | claimed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | claimed |